Clinical and radiological findings in methadone-induced delayed leukoencephalopathy

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Clinical and radiological findings in methadone-induced delayed leukoencephalopathy.

OBJECTIVE To increase awareness of the incidence of delayed leukoencephalopathy in rehabilitation medicine. SUBJECT A 34-year-old male patient in an inpatient neuro-rehabilitation clinic who developed cognitive, psychological and physical deterioration 33 days after methadone intake. METHODS Clinical follow-up for 7 months, brain imaging with magnetic resonance imaging and computed tomograp...

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Objective. To describe the clinical, radiological and pathological findings in a patient with methadone-induced delayed posthypoxic encephalopathy (DPHE). Case Report. A Thirty-eight-year-old man was found unconscious for an unknown duration after methadone and diazepam ingestion. His initial vitals were temperature 104 degree Fahrenheit, heart rate 148/minute, respiratory rate 50/minute, and b...

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BACKGROUND Toxic leukoencephalopathy has been described with inhalation and intravenous consumption of heroin and cocaine. The clinical picture varies widely but the imaging and histological features are characteristic. Magnetic resonance imaging (MRI) typically reveals diffuse bihemispheric white matter lesions. Histologically there is extensive spongiform degeneration of the cerebral white ma...

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Methadone-induced toxic leukoencephalopathy: MR imaging and MR proton spectroscopy findings.

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ژورنال

عنوان ژورنال: Journal of Rehabilitation Medicine

سال: 2014

ISSN: 1650-1977

DOI: 10.2340/16501977-1820